Prognostic significance of c-Met expression in glioblastomas

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Prognostic significance of c-Met expression in glioblastomas.

BACKGROUND The authors investigated whether expression of c-Met protein in glioblastomas is associated with overall survival and biologic features representing tumor invasiveness in patients with glioblastomas. METHODS Paraffin-embedded specimens of glioblastomas from 62 patients treated in a single institution were assessed by immunohistochemical (IHC) analysis of c-Met expression. On the ba...

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BACKGROUND The prognostic value of c-Met in breast cancer remains controversial. A meta-analysis of the impact of c-Met in breast cancer was performed by searching published data. METHODS Published studies analyzing overall survival (OS) or relapse free survival (RFS) according to c-Met expression were searched. The principal outcome measures were hazard ratios (HRs) for RFS or OS according t...

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Diagnosis and Prognostic Significance of c-Met in Cervical Cancer: A Meta-Analysis

OBJECTIVE A meta-analysis was conducted to analyze c-Met expression in cervical cancer. METHODS Articles related to our study were retrieved from PubMed, Elsevier, and China National Knowledge Infrastructure. State 12.0 was used for literature review, data extraction, and meta-analysis. The random-effects model and fixed-effects model were utilized to pool the relative ratio based on the hete...

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Clinicopathological and prognostic significance of c-Met overexpression in breast cancer

BACKGROUND c-Met has been shown to promote organ development and cancer progression in many cancers. However, clinicopathological and prognostic value of c-Met in breast cancer remains elusive. METHODS PubMed and EMBASE databases were searched for eligible studies. Correlation of c-Met overexpression with survival data and clinicopathological features was analyzed by using hazard ratio (HR) o...

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ژورنال

عنوان ژورنال: Cancer

سال: 2008

ISSN: 0008-543X

DOI: 10.1002/cncr.23972